In a study published by the Journal of Neurology, Neurosurgery, and Psychiatry4, a positive association between elevated levels of homocysteine and mood concerns was found, indicating that subpar folate metabolism and methylation have direct implications for neurological well-being. While research on the exact mechanisms of B vitamins, brain health, neurotransmitters, and methylation is ongoing, the science is clearโhealthy methylation makes for a healthy nervous system.*ย