Bioiberica’s hyaluronic acid improves aesthetic markers for aging skin: Study

Dermial has been designed to improve the effects of standard HA, Daniel Martínez-Puig, head of R&D human and animal health told NutraIngredients, and the new research has shown visible improvements to aging skin.

The first human clinical trial to be conducted with the ingredient investigated the effect of either 60 mg/day Dermial or placebo in 60 women between the ages of 35 and 65 over 12 weeks.

The results, yet to be published, suggested supplementation improved skin hydration and reduced wrinkles. 

Healthy aging skin

Hyaluronic acid is gaining increasing consumer and industry attention; according to FMCG Gurus Healthy 2022 aging skin report, 34% of consumers associate the ingredient with skin health, and the hyaluronic acid personal care product market is forecasted to grow by 8% between 2023 and 2033, according to Future Market Insights data.

The naturally occurring polysaccharide is present in the dermis and epidermis of the skin where its main function is to bind water to collagen, trapping water and maintaining skin hydration. 

Levels of hyaluronic acid decrease with age, which can lead to loss of elasticity, increased dryness and fragility. This infers the need for supplementation, Martínez-Puig noted, explaining that hyaluronic acid supplements are absorbed in the intestines and accumulate in the connective tissue, including in the skin.

Dermial contains a high concentration of HA (60-75%), plus other constituents such as sulfated glycosaminoglycans and collagen, designed to work in synergy and offer improved results to standard HA supplementation. Previous research​ indicates that Dermial could improve type I collagen by 48% in comparison to fermentation-origin HA.



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