[ad_1]
According to Grand View Researchโ, the global polyphenols market was valued at $1.68 billion in 2022 and projected to grow at a compound annual growth rate of 7.4% to 2030. Popular sources of polyphenolsโa class of more than 8,000 compounds found in many plant foodsโinclude grape seed, green tea, apple, citrus, olives, berries, cocoa and coffee beans, algae and pomegranate.
The companies NutraIngredients-USA spoke with for this article noted that market growth for their polyphenol-based ingredients and brands is overwhelmingly positive.
Marcos Lopez, U.S. regional director at Spanish botanical ingredient manufacturer Monteloeder, said the companyโs weight management ingredient Metabolaidโa combination of lemon verbena and hibiscus flower extractโcan be found in more than 70 finished products around the world, mostly in the form of food supplements.
โMetabolaid is our top ingredient, and itโs having an excellent performance,โ he said. โMany brands have trusted our ingredient already across the globe, from MLM, D2C and retail to practitioner brands, with great acceptance among their consumers.โ
Luxury and lifestyle brand Bella Grace Global is one of Monteloederโs customers. The Florida-based company uses the polyphenol-packed properties of Metabolaid (in addition to Nutrition21โs Chromax) in its new BellaTrim product, which launched last year timed to the holidays.
โLaunching a weight management product in late October, just before the holiday season and its associated overeating, was deliberate but certainly unusual,โ said Mark Miller, chief innovation officer at Bella Grace Global. โIt allowed us to engage in the January health and weight management goals with a plethora of testimonials, positive vibes and enthusiasm. To this extent we have had trouble keeping up production as sales have been robust and continue to climb.โ
French company Fytexia also employs citrus polyphenols for its weight management ingredient Sinetrolโa combination of grapefruit and sweet orange extracts, 26 other flavanones, 13 additional phenolic compounds and caffeineโsold in more than 50 countries.
โHundreds of brands worldwide chose Sinetrol as the core component for their dietary supplement formulationโฆputting the accent on quality and a consistent scientific dossier,โ said Laure Nogier, marketing operations manager of the botanicals business unit at Fytexia.
The scienceโ
Among the companies NutraIngredients-USA interviewed, spokespersons cited some combined 70 scientific papers backing the efficacy of their polyphenol-based ingredients or products.
According to a 2020 review published in Future Foodsโโ, most of the beneficial properties of polyphenols are โbelieved to be contributed by their free radical scavenging ability forming stable complexes and blocking further chemical reactions.โ
Polyphenols impart anti-obesity functions by reducing the digestion of carbohydrates and fats lowering energy intake, the researchers wrote. The compounds also stimulate energy expenditure, appetite suppression, inhibit the formation of fat cells from stem cells, regulate lipid metabolism and modulate the gut microbiota.
The researchers drew a comparison between the incidence of obesity a decade ago among adults in Japan (3.7%) and European countries (9.8โ24.8%). They suggested that the lower rate of obesity in the Japanese population may be due to higher levels of dietary polyphenol intakes reported at 1,500 mg per day (79% of which came from drinking green tea and coffee). In European countries, consumption was 283 to 1,100 mg per day.
โPlant-based phenolic compounds suppress appetite either by slowing down secretion of appetite-stimulating hormones, modulating MCH receptors [implicated in appetite and/or energy homeostasis] or by inactivation of appetite sensors,โ the researchers explained.
Acting on body compositionโ
Explaining how Sinetrol works to alter body composition, Fytexia says that it takes advantage of a process called adipose beiging. This is where white adipose tissue assumes the characteristics of brown adipose tissue, which is highly metabolically active and specialized for burning calories to produce heat.
โThis process has been suggested as a promising strategy to combat excess fat mass,โ Nogier said. โMoreover, the lingering effects of Sinetrol are proven: changes in body composition continued even 30 days after the cessation of the supplementation.โ
French ingredient supplier ActivโInside focuses on body composition as well with GrapโInside 15V, a patented whole grape extract with polyphenol and flavanol monomers, including ฮต-viniferin and epicatechin, which holds promise for the reduction of cellulite, body weight, fat mass and waist circumference.
โAs consumers increasingly focus on natural and science-backed solutions for health and wellness, GrapโInside 15V appears to align with these preferences, offering a standardized extract that could play a beneficial role in supporting individuals on their weight management journey,โ said Maitรฉ Jeanroy, marketing and communications manager at ActivโInside.
Grape extracts, marketed for weight management, often highlight properties related to highly bioavailable monomeric polyphenols where up to 82% of epicatechins are absorbed, Jeanroy added.
A metabolic โswitchโโ
Some supplements offer a one-two-punch to combat obesity. Monteloederโs Metabolaid promotes both satiety and fat burning components by focusing on AMPK, or AMP-activated protein kinase, which plays crucial roles in regulating growth and reprogramming metabolism.
โAMPK acts like a metabolic switch in our cells,โ Lopez said. โWhenever we need to consume energy, our body activates the AMPK pathway cascading into increased energy consumption and causing body fat to be โburned offโ. For this reason, it has been considered as a therapeutic target to treat obesity.โ
Another important factor to consider is the mechanism by which the human body controls energy intake, or calories, through hormonal signaling. Overweight individuals can generate a resistance to certain hormones involved in the sensation of hunger or satiety.
โOur clinical research evidenced that individuals taking Metabolaid felt satisfied with their diet and felt less hungry during the day,โ Lopez added. โThis coincided with an increase in GLP-1, which is a hormone released in the gut to induce satiety, as well as a glucose regulator.โ
Simultaneously, leptin hormone levels, related to appetite control as well as fat storage, were decreased.
โOverweight individuals tend to experience a decrease in their metabolism making [the weight management] process less efficient,โ he said. โBut luckily it is not something irreversible. Actions can be taken to get the metabolism back on track.โ
[ad_2]
Source link