Omega-3 levels linked to prevalence of frailty in older adults

The cross-sectional study drew on data from the UK Biobank, a large population-based cohort of participants between the ages of 40 and 69, recruited from 22 assessment centers between March 2006 and December 2010 in England, Scotland and Wales.

โ€œFrailty is a common geriatric syndrome characterized by unintentional weight loss, exhaustion, slow walking pace, low physical activity and low grip strength, which results in adverse health outcomes including falls, fractures, hospitalization, disability and death,โ€ the researchers noted. โ€œAs populations age, the prevalence of frailty increases rapidly, ranging from 12% to 24% in 62 countries around the world.โ€

Supported with funding from the National Research Foundation of Korea, the study was carried out by researchers from Hanyang University, The Fatty Acid Research Institute, University of Illinois and Sanford School of Medicine.

Omega-3s and frailtyโ€‹

This latest research builds on findings that associated circulating levels of omega-3 polyunsaturated fatty acids (PUFAs) with frailty among Koreans, a population with a high intake of fish.ย ย 

Previous studies have also reported an inverse correlation between frailty and fish intake in anย elderly rural coastal population in Ecuadorโ€‹, inย Irish elderly community-dwelling adultsโ€‹, inย Japanese older womenโ€‹ย consuming more than three to seven servings of fish a week and in an olderย Spanish populationโ€‹ย that included fish as part of a Mediterranean Diet.ย Chen et alโ€‹ย reported that frail older adults had lower use of fish oil compared to non-frail older adults in Taiwan.

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