Probiotic blend may boost sleep quality: Human study

The study uses Probioticalโ€™s Bifizen blend of Limosilactobacillus fermentumโ€‹ LF16 (DSM 26956), Lacticaseibacillus rhamnosusโ€‹ LR06 (DSM 21981), Lactiplantibacillus plantarumโ€‹ LP01 (LMG P-21021) and Bifidobacterium longumโ€‹ 04 (DSM 23233).

Data from the Pittsburgh Sleep Quality Index (PQSI, a subjective measure) indicated that the probiotics led to greater PQSI global scores than the placebo, while measurements from Fitbit wearable devices (objective measures) revealed strong trends toward greater sleep duration and total time in bed.

The study was co-sponsored by Italyโ€™s Probiotical and US-based Ashland. Probioticalโ€™s CEO Vera Mogna welcomed the trialโ€™s findings.

โ€œLack of quality sleep affects health, mood, and overall well-being,โ€ she said. โ€œThese results represent an encouraging solution and represent an exciting direction for the probiotics industry. Probiotical remains committed to studying the gut-brain axis and investigating the positive impact of beneficial probiotics on quality of life.โ€ย 

Sleep โ€“ the opportunityโ€‹

Between 10%ย and 30% of the global population are estimated to suffer from insomnia. According to the CDC, sleep deprivation is estimated to cost the US about $400 billion every year.

As reported by NutraIngredients-USAโ€‹, sales of supplements to support healthy sleep experienced a boom during the pandemic years to hit $737 million in 2021. There was some recalibration in the market after the record setting years of 2020 and 2021, but sales were still over $700 million in 2022, according to data from SPINS on the mass and natural channels.

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