Study explores neuroprotective effect of polyphenols in cyclists

Writing in the journal Nutrientsโ€‹,ย researchers from the University of Auckland andย The Eastern Institute of Technologyย investigated the effects of supplementation with either a phytonutrient blend or placebo in 10 male cyclists following high-intensity interval exercise performed during ozone exposure.ย 

โ€œSerum BDNF levels increased following an acute bout of high-intensity exercise in an ozone-polluted environment,” they wrote.ย โ€œIn addition, supplementation with an anthocyanin-rich supplement providing 4.3 mg/kg anthocyanins daily for 7 days resulted in significantly higher BDNF levels post-exercise compared to placebo.โ€ย 

The research was funded by the High Value Nutrition (HVN) Ko Ngฤ Kai Whai Painga National Science Challenge,ย a 10-year project to grow the science excellence and knowledge in support of food and beverage exports in Aotearoa, New Zealand.ย The supplement used in the study is manufactured by แพนrepa, a cognitive health company that markets brain drinks, shots, capsules and powders “designed and tested by neuroscientists”.

Polyphenols, exercise and ozone exposureโ€‹

Tropospheric ozone, a component of urban air pollution, isย generated through photochemical reactionsโ€‹ย involving hydrocarbons, nitrogen oxides and volatile organic compounds.

A highly reactive oxidizing molecule, it has adverse effects onย respiratoryโ€‹, cardiovascular andย central nervous systemsโ€‹, with links to neurological disorders such asย Alzheimer’s and Parkinson’s diseaseโ€‹,ย cognitive impairmentโ€‹,ย dementiaโ€‹ย andย neuroinflammationโ€‹.

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