The ‘promising’ role of saffron in stress resilience

In addition, levels of adrenocorticotropic and corticosterone hormones involved in the stress response were significantly reduced in the Affron group compared to rats exposed to stress only.

โ€œThese findings scientifically confirm the efficacy of Affron in improving occasional stress and anxiety, paving the way for the development of new natural supplements in line with current market trends,โ€ Carlos Rodriguez, communication manager at Pharmactive, told NutraIngredients. โ€œSecondly, the mechanism of action detailed in the study provides a deeper understanding of how Affron’s active components interact at the biological level, which may serve to improve the efficacy and safety of existing products and encourage innovation in the formulation of new supplements.”

He added that this research, published in the journal Nutrientsโ€‹,ย may increase the confidence and scientific perception of cognitive health supplements among both consumers and health professionals, promoting their acceptance and use for cognitive health.

Nutrition and chronic stress โ€‹

In an era where chronic stress has become an alarming public health concern, there is a need for sustainable, long-term solutions to meet the growing prevalence of mental health conditions. Exposure to diverse stressors over long periods can result in a cascade of adverse physiological and psychological responses, resulting in the progression of conditions such as anxiety and depression, as well as cognitive and emotional impairments.

Stress resilience is crucial to the management of stressors and preventing the development of chronic health issues, with allostasis playing in key role in this process. This involves the active maintenance of stability via the hypothalamic-pituitary-adrenal (HPA) axis.



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